Word: inhibitor
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...inexpensive and environmentally harmless rust inhibitor (under patent by chemist J. Anthony von Fraunhofer...
Both ritonavir and indinavir belong to a promising new class of drugs called protease inhibitors, which block production of a key enzyme, protease, that the virus needs to replicate itself. It was only last December that the U.S. Food and Drug Administration approved the first protease inhibitor, Hoffmann-La Roche's saquinavir. Ritonavir and indinavir could get the FDA go-ahead--and reach doctor's offices--as early as this summer. "The data are as good as anything I've seen," says Dr. Anthony Fauci, a leading AIDS expert at the National Institutes of Health...
...well be that the more sophisticated and effective HIV treatments become, the fewer people will have access to them. This grim new calculus is painfully apparent to Patrick Roll, 41, of Boston, whose T-cell count has dropped below 50 and who takes nine capsules of the protease inhibitor saquinavir each day. Considering that he first tested positive in 1983, he is in remarkably good health. "I'm from a socioeconomic group that had careers," he notes. "We've been able to keep our insurance or afford to take it on ourselves." Not everyone is as fortunate as Roll...
...spectrum of possibilities for a relatively low-toxicity and highpotency inhibitor of cell proliferation is tremendous," he said...
Researchers at Children's Hospital say that a purified inhibitor, obtained from the serum and urine of tumor-bearing mice, was found to stop anglogenesis...