Word: inhibitors
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Dates: during 1990-1999
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...Soon ACE inhibitors, a widely used high-blood-pressure medication, may be added to the roster of pills taken by folks at risk for a heart attack. A major study, released ahead of schedule to get out the good word, shows that daily doses of the ACE inhibitor ramipril led to a dramatic 25% decline in heart attacks and strokes among diabetics and patients with a history of heart disease. Cost: 85[cents...
...first, scientists could not develop angiogenesis inhibitor drugs because there was no established test for the drugs' effects on the growth of blood vessels...
Three years after his initial discovery, in 1975, Folkman and colleague Henry Brem discovered the first angiogenesis inhibitor molecule in cartilage. Researchers, including Folkman, had to learn to culture blood vessels and try to test angiogenesis inhibiting compounds...
...Ingber himself who, as a post-doctoral fellow, discovered the drug TNP-470, the first angiogenesis inhibitor from Folkman's lab to enter human clinical trials...
...meantime, I've gone on a so-called proton-pump inhibitor, a new kind of prescription drug that cuts down on acid production. I've also been given a list of changes to make in my life-style. Let's see: I don't drink or smoke or eat fatty foods, so I can't really stop. I'm not obese or even a little overweight, so losing weight won't help. That leaves giving up my beloved caffeine and my even more beloved bedtime snack. We'll see. I'm not making any promises...