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...ALZHEIMER'S DISEASE Scientists began safety testing the first drug designed to tackle the root cause rather than the symptoms of this brain-addling disease. Patients in the early stages of Alzheimer's were given a gamma secretase inhibitor, a compound that blocks the formation of the sticky plaques that gum up the brain's neural connections. So far, the drug seems to have been well tolerated...

Author: /time Magazine | Title: Your A to Z Guide to the Year in Medicine | 1/6/2001 | See Source »

...remission. In the most recent results, 30 percent showed no chromosomal sign of disease and appeared to have been cured. "This drug is amazing," says Richard Stone, an oncologist at Dana-Farber Cancer Institute, in Boston, who has been testing Glivec (also known as an STI, for signal transduction inhibitor). "Even patients who are near death, at the end stage of this disease, are going into remission...

Author: /time Magazine | Title: A Virus That Kills Cancer | 12/18/2000 | See Source »

...idea that Alzheimer's might be at least somewhat preventable--if not by mental gymnastics, then by chemistry--has attracted lots of interest. The National Institute on Aging launched a research trial to see if anti-inflammatory drugs, such as naproxen or the COX-2 inhibitor Vioxx, can delay onset. Another study compares the Alzheimer's drug Aricept with vitamin E to see if the latter can ease cognitive problems. But these are all preliminary explorations of intriguing clues and don't yet apply to everyday life...

Author: /time Magazine | Title: Brain Gymnastics | 5/15/2000 | See Source »

...combining the traditional chemotherapy drugs with an experimental drug that attacks the tumor's blood supply. According to the report, 84 percent of mice with tumors that were unresponsive to traditional chemotherapy drugs were cured when the standard chemotherapy drug was combined with a low dose of an angiogenesis inhibitor...

Author: By Sasha A. Haines-stiles, CRIMSON STAFF WRITER | Title: HMS Researchers Use New Technique To Cure Cancer in Mice | 4/5/2000 | See Source »

...inhibitor, TNP-470, doesn't attack the tumor itself but instead targets the blood vessels...

Author: By Sasha A. Haines-stiles, CRIMSON STAFF WRITER | Title: HMS Researchers Use New Technique To Cure Cancer in Mice | 4/5/2000 | See Source »

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