Word: inhibitors
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...present in tears and saliva, is found in abnormal amounts in the stomachs of ulcer patients, seems to be produced in extra-large quantities during emotional upsets. The researchers hope that a cure for ulcers may be found in chemicals that inhibit the enzyme (they have already found one inhibitor: dodecyl sulfate...
...recent experiment was to put a "growth inhibitor" (iodoacetic acid) in the water. It did not kill the cells, but stopped their growth by breaking a necessary chain of chemical reactions. Then, one after another, Thimann added likely compounds, hoping to see growth start again. He found that malic acid (which is found in apples) would overbalance the evil influence of iodoacetic acid, allowing the cells to grow. This proved that malic acid was somehow involved in the chain of reactions which the inhibitor had broken...
...animals. They also found an activator in the blood plasma which enabled renin to work. The combination of renin and this activator was dubbed angiotonin. As a working hypothesis, angiotonin was marked as the chemical cause of high pressure. Further experiments showed that normal kidneys probably manufacture an "inhibitor" substance, which destroys or neutralizes surplus angiotonin, keeps the pressure within normal bounds. Two research teams, including Dr. Page's in Indianapolis, recovered from kidney extract inhibitors which lowered the pressure of animals 50 to 100 points...
Then, at last, it was time to see whether the inhibitors would give relief to hypertensive humans. For the past year 17 lucky patients of Dr. Page's have been getting inhibitor injections. In general, their pressures have been lowered and kept down, their headaches, chest pains and shortness of breath have disappeared, "their feeling of well-being is evident." Hypertensives with impaired vision due to blood congestion in the eyes have been greatly improved...