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...doing atop the world's largest drug company? Saving it in court. The company is facing a flood of legal challenges. Among them: drugmaker Novo Nordisk recently claimed patent infringements for Pfizer's upcoming inhaled-insulin drug, Exubera, and Pfizer is being sued over Celebrex, its controversial Cox-2 inhibitor pain medication. Bonus points: Kindler knows his way around Washington, which should help Pfizer navigate the regulatory swamp. He has some operations cred too. At McDonald's, he led the turnaround of Boston Market...

Author: /time Magazine | Title: People to Watch In International Business | 8/20/2006 | See Source »

Research at the institute uses genetic data from the recently completed human genome project to better understand the underlying chemistry of disease. One project team is currently attempting to build an inhibitor for every human gene, and researchers just completed a catalog of human genetic variation called the Haplotype...

Author: By May Habib, CRIMSON STAFF WRITER | Title: Couple Doubles Gift to Genome Institute | 12/1/2005 | See Source »

...because they were “impressed with the progress and wanted to see it accelerated.” Research at the institute uses genetic data from the recently completed human genome project to better understand the underlying chemistry of disease. One current project is attempting to build an inhibitor for every human gene, and researchers just completed a catalog of human genetic variation called the Haplotype Map. “I’m just a humble social scientist so I don’t understand all of this,” said Summers during his remarks...

Author: By May Habib, CRIMSON STAFF WRITER | Title: Broads Double Contribution to Genome Institute | 11/30/2005 | See Source »

...Does the phrase "water pill" ring a bell? Three years ago another big NIH study showed that a cheap, old-fashioned diuretic (a.k.a. water pill) worked better for most folks with high blood pressure than did costly, cutting-edge medications. (These included a calcium-channel blocker and an ACE inhibitor). Then there's the sad lesson of Vioxx and its ilk. That category of painkillers captured a $5 billion-a-year market on the celebrated promise that they were safer than older, cheaper analgesics like Tylenol or Advil. In this case, as the nation learned when Vioxx and Bextra were...

Author: /time Magazine | Title: Viewpoint: Why New Drugs Don't Live Up to the Hype | 9/30/2005 | See Source »

...actor, an evil conspirator that helps build the new blood supplies that tumors need to grow. COX-2 also makes cancer cells more resistant to the body's immune response and more resistant to drugs. What would happen, scientists wondered, if you suppressed the COX-2 enzyme with an inhibitor such as Celebrex? "It makes sense that if you shut off the prostaglandin by turning off the COX-2, then the other things wouldn't happen," says Altorki. "The science is so strong, so persuasive...

Author: /time Magazine | Title: My Most Difficult Choice | 5/16/2005 | See Source »

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