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...specific enzyme on which Dr. Innerfield has been working is trypsin, a secretion of the pancreas. In some situations, claims Dr. Innerfield, trypsin can be the answer to a doctor's prayer. As a therapeutic agent, it effectively speeds up the body's host reaction to injuries. Moving in the blood stream to an area of inflammation, trypsin can stimulate the white corpuscles there to prodigious feats of valor against invading organisms...

Author: /time Magazine | Title: Medicine: Enzyme Treatment | 1/18/1954 | See Source »

...running medical fight over the therapeutic value of enzymes as natural catalysts (TIME, July 13), the leading spokesman for the affirmative fired off some new evidence last week. Dr. Irving Innerfield of New York Medical College told the Toledo Academy of Medicine that new methods of administering enzymes to patients are safer than the old, and no less effective in speeding recovery from a variety of diseases, including thrombophlebitis, diabetes, rheumatic fever, arthritis and acute eye infections...

Author: /time Magazine | Title: Medicine: Enzyme Treatment | 1/18/1954 | See Source »

...first Dr. Innerfield and his associates at Manhattan's Flower and Fifth Avenue Hospital gave trypsin to patients by intravenous drip. Other medical researchers objected that this method was unsafe, and a possible cause of blood clots. While not expressly conceding the point, Inner-field worked out another way of administering trypsin-intramuscularly...

Author: /time Magazine | Title: Medicine: Enzyme Treatment | 1/18/1954 | See Source »

...Innerfield cautions that trypsin must be used with care, and only in cases of acute inflammatory reaction where the cells undergoing changes are not irretrievably damaged. If this is done, he told his Toledo audience, intramuscular trypsin is "safe and effective." Asked one doc- tor: What about using trypsin for coronary thrombosis, a disease for which it was once thought to be valuable? Answered Researcher Innerfield, who is just beginning a long series of tests in this matter: "In three years I hope to be able to help...

Author: /time Magazine | Title: Medicine: Enzyme Treatment | 1/18/1954 | See Source »

Since the Innerfield article appeared in the A.M.A. Journal, doctors and laymen all over the U.S. have been bombarding Chicago's Armour Laboratories with requests for the purified form of trypsin. The laymen, and most doctors, will get none. Actually, more than 40 research groups have already worked with trypsin, and none has had as much success as Dr. Innerfield in dissolving clots. Some agree that it cuts down inflammation, but so do other things which are safer. The research will go on, and some day the contradictions will be resolved. Meanwhile, the dawn of the age of enzymes...

Author: /time Magazine | Title: Medicine: Enzymes & Doubts | 7/13/1953 | See Source »

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