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...enzymes-some of nature's complex chemicals which act as catalysts in countless physiological reactions. A star among the enzymes was expected to be trypsin, secreted by the pancreas. It was known to dissolve dead tissue around wounds, but a team of Manhattan researchers led by Dr. Irving Innerfield made far more dramatic claims...

Author: /time Magazine | Title: Medicine: Enzymes & Doubts | 7/13/1953 | See Source »

...A.M.A. Journal has published a full-dress report by Innerfield & Co., and the argument is on. Other researchers using similar methods have tried to duplicate Dr. Innerfield's results and have failed utterly. In fact, say some, trypsin is too dangerous to be used at all in many of the cases for which Dr. Innerfield recommends...

Author: /time Magazine | Title: Medicine: Enzymes & Doubts | 7/13/1953 | See Source »

...first, trypsin was used mainly in wound dressings or in local injections to clear infections in the chest. Lately, in purified form, it has been injected into veins and muscles. Dr. Innerfield dripped it into the veins of rabbits and dogs and concluded that it was safe; large doses, he said, had a powerful effect in preventing the formation of blood clots and dissolving those already formed. He has since given it to 428 patients with 52 different complaints and, he says, with good effect in nearly all: reduction of inflammation and swelling in arthritis, dissolution of blood clots...

Author: /time Magazine | Title: Medicine: Enzymes & Doubts | 7/13/1953 | See Source »

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