Word: insulin
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Dates: during 1950-1959
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...famed Physiologist Jacques Loeb, discoverer of artificial parthenogenesis, Robert Loeb left the University of Chicago after his sophomore year in 1915 to enter Harvard Medical School, graduated magna cum laude. After residency at Johns Hopkins, Loeb switched to Manhattan's Presbyterian Hospital in 1921, helped administer the first insulin treatment for diabetes, pioneered in electrolyte physiology, discovered the first effective treatment for Addison's Disease. In 1947 he became Presbyterian's medical service director, in the same year Columbia's chief medical professor. No narrow specialist (he belongs to the American Philosophical Society), Loeb...
Three years ago there was not a single antidiabetic drug that U.S. doctors could prescribe generally, and of two under test, one (carbutamide) was dropped for fear of liver damage. Diabetes victims were slaves to insulin and the needle. Last week 515 experts gathered in Manhattan under the auspices of the New York Academy of Sciences for the second symposium in seven months on the several drugs now being promoted: three on general prescription,* three being tested on patients under research safeguards...
...oral drugs do not always take the place of insulin, though they may reduce the need for injections by either 1) stimulating the release of natural insulin from a sluggish pancreas, or 2) increasing the effectiveness of natural or injected insulin...
...biguanides, the Joslin Clinic's Dr. Leo P. Krall conceded (after trial in 244 patients) that they "are capricious unless the physician uses them with special understanding." But he insisted that DBI, given along with reduced doses of insulin, has helped some unstable diabetics to lead a more normal life than they could when they took insulin several times a day. Main trouble: there is a narrow margin of safety between the DBI dose needed to control the blood sugar level and the dose that may produce side effects, so treatment in severe cases should begin in a hospital...
Barber, a diabetic, had taken insulin at 10:30 a.m. on the morning of the day of the accident. Dr. John C. Wells, associate physician of the University Health Services, testified that at the time of the accident the insulin would have had its maximum action...