Word: insulin
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Dates: during 1980-1989
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...Insulin and a sleeping beauty
...true-life tale that has scandalized the gentry. The final chapter began to unfold last week in Newport, R.I., where jury selection was nearly completed in the trial of Claus von Bülow, 55. He is accused of attempting to murder his heiress wife Martha with injections of insulin, precipitating the coma in which she has languished for more than a year. She is not expected to recover. During the quizzing of prospective jurors, the trial produced its first titillating revelation: Von Bülow had been having an affair with another woman...
...Clarendon Court that two murder attempts were supposedly made. The prosecution alleges that in December of 1979 and again in December of 1980, Von Bülow gave his wife, who suffered from chronic low blood sugar, shots of insulin, the hormone that helps metabolize sugar. Excess insulin would have dropped her blood sugar dangerously low. Sunny was hospitalized for a few days the first time and permanently the second; she is now in the Harkness Pavilion at Columbia-Presbyterian Medical Center in Manhattan. The seed of scandal was planted when Sunny's maid of 23 years, Maria Schrallhammer...
Kissebah found otherwise. When the women were tested, significant differences between the groups appeared. While women of normal weight and those with lower-body-obesity fell within the normal range on the tests, all of those with upper-body-obesity had high blood levels of insulin, sugar and fats, common indexes of diabetes. Furthermore, when glucose-tolerance tests were given, 15 out of the 25 scored within the diabetic range. Statistically, says Kissebah, the group was eight times as likely as normal women to develop the symptoms of the disease...
Preliminary studies at Wisconsin have also shown that the overpacked fat cells have a smaller number of the receptors to which insulin attaches, controlling the utilization of sugar. This may account for the elevated levels of blood sugar and insulin. The tendency to acquire oversize fat cells may in turn be regulated by hormones, suggests Kissebah. Women with upper-body obesity, he found, have a higher ratio of male hormones to female hormones than their lower-body-obese counterparts or women of average weight. The very distribution of their adipose tissue-around and above the waist-is more like that...