Word: insulin
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Dates: during 1990-1999
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...Zone. They scoff at Sears' contention that ancient people shrank in height after the invention of bread. "Give me a break," says Bonnie Liebman, director of nutrition at the Center for Science in the Public Interest. "Those kinds of statements are not good science." What about the insulin-makes-you-fat thesis? "Ridiculous," says Stanford University endocrinologist Gerald Reaven. The secret to weight loss, he says, still lies with cutting calories. In fact, skeptics argue, when Zone dieters do lose weight, it's only because the Zone's rigid calculus delivers a high-bulk, low-calorie diet--hardly a revolutionary...
Sears' approach goes against the grain in more ways than one. His books contradict the prevailing orthodoxy of high-carbohydrate, low-fat diets. He contends that an excess of carbs forces the body to overproduce insulin, a hormone that promotes fat storage. The Zone doesn't forbid all carbs--high-fiber fruits and vegetables are fine--but it does discourage all the tastier ones. Like pasta, rice and bagels. Sears' position: Get over it. "If all bread left the face of the earth, we'd have a much healthier planet," he declares...
Abhinav Seth '98, who is also applying to MD-Ph.D. programs, is broadening his research skills by studying how insulin can be affected by the levels a drug that alters the proteins that control insulin expression...
...Sippe Schat, a doctor from northern Friesland, goes on trial later this month for the alleged murder of a 72-year-old cancer patient who had seemed in good spirits just before she died in a nursing home. According to prosecutors, Schat simply gave her a lethal shot of insulin without consulting anyone and left her to die alone, allegedly telling a nurse as he left, "If she hasn't died by 7 a.m. tomorrow, give me a call...
...discovery of DNA itself, a result of basic research. When Francis and Crick searched for DNA, they had no idea of the possibilities ahead. However, without their discovery, bacteriophages and insertion of human genes into bacteria would not be possible or even thinkable. This process now produces human insulin within bacteria, thus allowing diabetics to avoid the side-effects of animal insulin and providing a cheaper source of the drug...