Word: insulin
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Dates: during 2000-2009
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...People [ask] me why I'm never depressed by this, and it's because I've learned. I built the first wearable [insulin] pumps, and people, including doctors, said, "They'll never let people out of the hospital, walking around getting drugs," and it went from "they'll never allow this to happen" to now its the standard of care. How many diabetics are out there that don't want to make sure they get good control [of their blood sugar] all the time. And it goes, again, from being indefensible to being indispensable...
...smuggle 53 items, including gifts to Russia's last Tsar, out of the Hermitage. A further 221 exhibits, worth some $5 million, remain missing, prompting President Vladimir Putin to order an inventory of all 50 million artworks kept in Russian museums. According to his lawyer, Zavadsky stole to buy insulin for his diabetic wife, whose curator's salary was well below the national average income. DIED. Robert McCullough, 64, who changed the U.S. civil-rights movement in 1961 when he refused to pay a $100 fine for requesting service, along with eight other black students, at a whites-only lunch...
...scientists discover an ideal source of healthy cell lines, there is still much to learn about how to coax them into turning into the desired kind of tissue. Parkinson's patients suffering from tremors caused by damaged nerves could benefit from replacement neurons, while diabetics who can't produce insulin could control their blood sugar with new pancreatic islet cells. But so far, no human ESCs have been differentiated reliably enough that they could be safely transplanted into people, although animal studies with human cells are under way. Not surprisingly, the groups closest to human trials are in the biotech...
...finally begin, there's no method for precisely determining whether the transplanted stem cells are functioning correctly. "If we transplanted cells to regenerate a pancreas," says Owen Witte, director of UCLA's Institute for Stem Cell Biology and Medicine, "we can measure in your blood if you're producing insulin, but we can't see whether the cells have grown or evaluate whether they might grow into a tumor." So scientists are seeking to develop marking systems that let them trace a transplant's performance...
...helped fund biotech start-up ES Cell International (ESI), home to Briton--and now Singapore resident--Alan Colman, who was part of the British team that cloned Dolly the sheep in 1996. ESI manufactures its own embryonic-stem-cell lines and is working on shaping those cells into insulin-producing pancreatic tissue and cardiac muscle, which could be given to patients suffering from diabetes or heart disease. It's exactly the kind of potentially profitable research Singapore wants, and the company hopes to begin clinical trials next year. As with most stem-cell work at Biopolis, the focus...