Word: insulin
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Dates: during 2000-2009
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...still not clear why diabetes and Alzheimer's should be related. One possibility is that the excess insulin the body churns out to try and control blood sugar inflames the blood vessels - which would also explain how diabetes leads to heart disease. But while it isn't yet exactly certain what's going on, the result is a kind of good news/bad news story. The bad news is that type 2 diabetes has been on a dramatic increase as Americans have gotten more obese over the past couple of decades - which means the Alzheimer's epidemic that's already expected...
...Your Drug Was Discontinued Eli Lilly was the last U.S. manufacturer of animal insulin, which is extracted from the pancreatic tissue of cows and pigs and has been used by diabetics for more than a half-century...
...identified that have a clear and defined response to diet and environmental or lifestyle choices," says Rosalynn Gill-Garrison, a molecular biologist who helped found the Sciona company in 2000. Worried about that caffeine-calcium link? Sciona tests for that, as well as genetic variants that affect insulin sensitivity, cholesterol levels and more...
...eggs, remove their nuclei and replace them with skin cells taken from diabetic patients at Columbia University. The resulting embryo will generate stem cells that Melton's group will extract and hopefully coax into becoming pancreatic islet cells. These could then be injected into the patient to generate the insulin that they lack. If Melton can perfect the technique, it will ultimately allow patients to create their own, customized treatments from their own stem cells...
...causing diabetes but that different body types, influenced by genes, respond to the same food differently," says Dr. William Hsu of the Joslin Diabetes Center. With no famine, these genes continue to convert food into glucose and fat. Excess glucose levels build up gradually in the blood, and insulin, which normally keeps glucose levels in check, can't keep up. After years of this metabolic treadmill, diabetes can develop...