Word: insulin
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...insulin gene was obtained from a rat tumer. Humans, however, use rat insulin in the treatment of diabetes...
Gilbert said three major problems now face insulin research teams across the nation...
Walter Gilbert '53, American Cancer Society Professor of Molecular Biology, said the insulin research may eventually lead to commercial production of several important proteins other than insulin--such as the human growth factor hormone--which are now available only in small quantities...
Although research teams in California last year achieved limited success in using gene-splicing techniques to induce bacteria to produce proteins, Gilbert's group was the first to induce bacteria to excrete a molecule as large as insulin...
Gilbert said that to insure the insulin would be excreted. the researchers inserted the insulin gene next to a gene for a protein the bacteria normally excreted. The insulin molecules rode "piggyback" on the excreted protein molecules across the bacterial membrane...