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Chemist Sanger worked with crystalline insulin, a comparatively simple protein. First he broke the large molecules by oxidation into two fragments, one containing 21 amino-acid building blocks, the other 30. Then by other methods (e.g., hydrolysis), he broke the two parts down until he had fragments that contained only a few amino acids each. These were compounds familiar to biochemists. Sanger identified them by paper chromatography,† and the first and easiest part of his job was done...

Author: /time Magazine | Title: Science: Protein Puzzle | 8/4/1952 | See Source »

...living things. This, they decided, must be a taillike fragment knocked off some larger fragment. They would shift it around, like a piece in a jigsaw puzzle, until they found a spot where it could be placed to form a familiar compound. Little by little, their picture of the insulin molecule took on detail. At last they were sure they knew where each building block belonged...

Author: /time Magazine | Title: Science: Protein Puzzle | 8/4/1952 | See Source »

...Knopp said he would do his best. From the old man's wife, waiting in the corridor, he learned that his patient was a diabetic, on insulin for ten years. While he went on with his examination, Dr. Knopp sent the woman off with her young neighbor to be interviewed by a social service worker...

Author: /time Magazine | Title: Medicine: Saturday Night | 2/25/1952 | See Source »

...Manhattan meeting of the New York Academy of Sciences heard last week about a drug that may have more effect on mankind than insulin or penicillin. The announcement dealt with work done by Dr. Eli D. Goldsmith, chairman of the academy's biology section, on a chemical that stops pregnancy in mice without doing any apparent harm to the animals. Given to the mice in their diets after they have become pregnant, it causes the fetus to be "resorbed" without any apparent harmful effect...

Author: /time Magazine | Title: Science: New Contraceptive? | 10/29/1951 | See Source »

...days before, the new King had been a patient in a mental hospital near Geneva, undergoing insulin shock treatments for an unspecified mental disorder, while his younger brother, Prince Naif, ruled as Regent. Then, so goes the story in Amman, Talal began getting word of a plot at home. Naif, deciding he liked the feel of power, was conniving with two cabinet ministers and Jordan's chief justice to dissolve Parliament and proclaim himself King. He would be backed by the guns of the Arab Legion's Hashemite regiment, the King's bodyguard...

Author: /time Magazine | Title: JORDAN: Friend or Foe? | 9/17/1951 | See Source »

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