Word: intercellular
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...space and can send waves of calcium signals from one spot to the other,” said Bacskai, who added that these results were independent of neuronal activity. Kuchibhotla said the researchers think that the plaque deposition may be seen as a traumatic event that is causing these intercellular calcium waves, providing a new line for Alzheimer’s therapy. “Modulating the activity of astrocytes might be an interesting therapeutic target slightly different than the neurocentric view,” said Kuchibhotla. Since this research can be applicable to other diseases—including Parkinson?...
Enter interferon. The initial infection somehow triggers the first cell into producing IF. In turn, the interferon assumes the role of an intercellular messenger; it passes through the cell membrane and moves on to warn surrounding cells of the viral invasion. The healthy cells respond by producing antiviral proteins, which meet any invader head on. The entering virus will not be able to replicate within the new cell; if it does manage to reproduce, its progeny find that they are unable to leave the cell. The cycle of infection is broken...
...effect of X-rays. An electric charge passing through a cell, said Dr. Failla, divides the molecules of protoplasm into positively and negatively charged particles. These ions then recombine to form new chemical substances. In a vain attempt to re-establish osmotic equilibrium in the cell, water from the intercellular spaces flows into the cell through the membrane, causing the cell to swell...
...then took the fluid containing the cell corpses, centrifuged and filtered it, added it to a suspension of normal cells. The "respiration" (oxygen intake) of these was observed to increase by 10%. It appeared that before they died the damaged cells secreted stimulating fluids which Dr. Sperti now calls "intercellular hormones...
...study of intercellular materials as solvents in the living animal for diffusable materials introduced into the blood stream at a rate faster than elimination can take place. There is much evidence that sugars diffuse into collagen to a point of equilibrium with the accumulation in the blood stream so that the studies should begin with sugars. It is possible that sugars may play a role in calcification of tissues. In any event, an attempt will be made to study calcified tissues, teeth, and bone. It is to be anticipated that progress will be slow as the techniques required will have...
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