Word: intracellular
(lookup in dictionary)
(lookup stats)
Dates: all
Sort By: most recent first
(reverse)
...swelling in the lungs, a result of the body's own immune-system response. In Hong Kong, doctors claim they are successfully combating the disease using the antiviral drug ribavirin to inhibit the virus combined with corticosteroids to check an overstimulated immune response. Ribavirin works by interfering with intracellular viral replication, slowing the infection's spread within the body. The problem, as microbiologist Professor John Tam of CUHK points out, is that "if you stop the replication, that means you stop the function of the cell...
...particular, he was fascinated by how the extracellular matrix—the jelly-like substance surrounding cells—affects intracellular processes. Much of Bernfield’s work involved the isolation and characterization of proteoglycans, proteins of the extracellular matrix with key roles in tissue development...
Their research focuses on glutamate, an excitatory neurotransmitter. Scientists had believed that it might be possible to limit cell death after a stroke by stopping glutamate from killing neighboring cells, but until now, little was known about the intracellular routes through which glutamate carries out its deadly "excitotoxic" effects...
Gelman said his research focused on combinatorial chemistry, which is a method for generating large molecules by mixing and matching smaller parts. Gelman said his research has applications in the areas of signal transduction, intracellular communication and pharmesutical design...
...Samuel Silverstein of Manhattan's Rockefeller University have found that it belongs to a select group of bacteria that evade the body's immune system by turning it to their own advantage. Like the microbes that cause tuberculosis and leprosy, the bug is what scientists dub an intracellular pathogen. It invades white blood cells called monocytes, which normally kill bacteria, and uses material within these cells to propagate-in droves. In one experiment at Rockefeller, Legionella added to a culture of monocytes increased 100,000-fold within days...