Word: intramuscular
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...Innerfield cautions that trypsin must be used with care, and only in cases of acute inflammatory reaction where the cells undergoing changes are not irretrievably damaged. If this is done, he told his Toledo audience, intramuscular trypsin is "safe and effective." Asked one doc- tor: What about using trypsin for coronary thrombosis, a disease for which it was once thought to be valuable? Answered Researcher Innerfield, who is just beginning a long series of tests in this matter: "In three years I hope to be able to help...
...into his office and called his assistant, 28-year-old Dr. Angelo Cresseri. He showed him a bottle of colorless liquid marked "Glutaril cas. 20%." It was a new formula, said Dr. Pauletta. He filled a large syringe with the liquid and ordered Assistant Cresseri to give him an intramuscular injection in the thigh...
...cured. In the test tube, histamine can be made by combining two well-known substances-vitamin C (ascorbic acid) and an amino acid called histidine. Would it work in the body? First on guinea pigs and then on his patients, Wirtschafter tried intravenous injections of vitamin C, followed by intramuscular injection of a histidine solution. Sure enough, it worked: blood tests showed an increase in histamine...
Doctors now know in general which diseases penicillin helps, have worked out a tentative schedule of dosage. Present consensus is that 40,000 to 120,000 units daily, given gradually by vein or intramuscular injection for about a week, should cure the average case with a systemic infection. Treatment for gonorrhea is usually much shorter; treatment for subacute bacterial endocarditis, much longer. For application to wounds, about 50,000 units in salt solution is used, varying with the size of the wound...
...their work is a military secret. No secret is the drug's use on Cocoanut Grove fire casualties (TIME, Dec. 7) at Massachusetts General Hospital. Each patient got sulfadiazine to prevent streptococcus infection on burned surfaces and then, if he still had a temperature six days later, intramuscular injections of 5,000 units of penicillin every four hours to prevent staphylococcus infection. It is notable that no patient so treated died of staphylococcus blood poisoning...