Word: iproniazid
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Dates: during 1957-1957
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Medical researchers reported last week that they have found a sort of untran-quilizer-a drug that shows promise in treating mental patients suffering from depression. It is no new chemical, but iproniazid (trade name: Marsilid), first cousin of isoniazid and a veteran of the 1951 campaign against tuberculosis. When it was given to TB patients at New York City's Sea View Hospital, they became happy, ate ravenously, gained weight and started dancing in the wards (TIME, March 3, 1952). Iproniazid was soon retired from widespread use because it produced undesirable side effects, such as dizziness, constipation, difficulty...
...ataraxics-drugs to help bring about mental wellbeing. They found plenty of tranquilizers, excellent for overactive, agitated patients, but none that was much good for those at the opposite end of the scale, suffering from depression; in fact, some tranquilizers induced worsened depression. Then researchers hit on half-forgotten iproniazid. At New York's Rockland State Hospital three doctors gave the drug to 14 patients suffering from depression for which there was no cause to be found in physical illness, got good results in twelve, had to stop the drug in two cases because of unfavorable side effects...