Word: ipse
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Daley, who is also a professor at Harvard Medical School, said that he and his colleagues created 20 stable iPS cell lines from patients with genetic diseases including Parkinson's, Huntington's, Down Syndrome, juvenile-onset Type I diabetes, and two types of muscular dystrophy.
Konrad A. Hochedlinger, a Medical School professor whose laboratory contributed the Lesch-Nyhan syndrome cell line to the project, said that the "iPS trick" will change the face of stem cell research.
Studying many diseases, especially degenerative diseases, often entails isolating cells that are not readily accessible, such as brain cells. But by deriving patient-specific iPS cells with the new technology, Hochedlinger said, researchers will be able to study the development of the disease in a lab dish.
Hochedlinger added that the iPS technology used in the research is still very new.
"HSCI scientists have been among the first to practice iPS technology," Daley said. "And HSCI has by far produced the most human iPS lines to date."