Word: ipse
(lookup in dictionary)
(lookup stats)
Dates: all
Sort By: most recent first
(reverse)
Unlike the technique used to create induced pluripotent stem (iPS) cells by genetically manipulating a patient's cells and reprogramming them into a pluripotent state before morphing into a different type of body tissue, direct reprogramming simply flips an adult cell directly into the desired form, skipping the middle steps...
Despite the relative efficiency of this approach, both Melton and Daley stressed that direct reprogramming does not eliminate the need to continue work with iPS cells or human embryonic stem cells (hES).
Scientists have long hoped to find a way to reprogram a patient's cells to produce new ones. Research with stem cells, and similar entities called iPS cells that were announced last year, has aimed to achieve this in a two-step process.
So, he says, someday scientists may be able to replace dead nerve or heart cells in people by converting some neighboring cells. At the same time, he stressed that it's still important to study embryonic stem cells and iPS cells.
"For the foreseeable future, human embryonic stem cells will remain the gold standard," said Daley, whose research is currently funded by the National Institutes of Health, HSCI, and other private sources. "Even with iPS cells, we will want to study the biology of embryonic stem cell derivation, which occurs from...