Word: iressa
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...gastrointestinal stromal tumors - for which there had been no effective treatments. In a matter of months, patients who were out of options had their lives back, and while their cancer was not cured, it was under control, at least for a while. Other new drugs, including Tarceva and Iressa, also halt tumor growth by messing with tyrosine kinase. The key to developing such drugs, says Glaspy, is "torturing cancer cells, and getting them to confess to us which pathways they are dependent...
...example, the anti-cancer drug Iressa effectively treats lung adenocarcinoma only in patients harboring specific mutations in one specific receptor...
Beginning examples of such genome-oriented cancer treatments such as Iressa have met with overwhelming success, according to Larry J. Thompson, communications director for the National Human Genome Research Institute (NHGRI)—one of the 27 institutes...
...attention-grabbing April Dana-Farber Cancer Institute study that explained why the lung cancer drug Iressa was so successful relied on Broad’s resources. Lander said it relied on Broad’s facilities to run a large-scale analysis that revealed a mutation in some lung cancer patients that dramatically increases their responsiveness to Iressa...
...press release said the group will also conduct research to determine whether targeted treatments will benefit patients for whom Iressa alone does not help...