Word: isentress
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Dates: during 2007-2007
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...second drug, an integrase inhibitor from Merck, aims to tackle HIV where it hurts the most - by blocking the integrase enzyme, which the virus uses to insert its genes into a host cell's genome and hijack the machinery to churn out more copies of itself. Called isentress, the experimental agent helped 75% of patients reduce their viral load of HIV to acceptable levels, compared with only 40% of patients given placebo...
...larger well of knowledge upon which they can draw. Yet, even as newer classes of ARVs arrive, drugs cannot be the only answer to AIDS. Already, says Dr. Roy Steigbigel of State University of New York at Stony Brook, and one of the leading investigators of Merck's isentress, volunteers have begun to develop resistance to the integrase inhibitor - a drug that hasn't even yet been approved...
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