Word: isoniazids
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...first medications more effective than the Asian ancients' chaulmoogra oil had been developed by U.S. researchers, tested at the Public Health Service Hospital in Carville, and just released for use in Hawaii. The best-known and most widely used is dapsone (DDS). For those who also had tuberculosis, isoniazid was used. Still newer drugs include the potent antibiotic rifampin, and even thalidomide, which is administered to treat complications, but not for women of childbearing age. Collectively, these are indeed wonder drugs: when used promptly to treat newly discovered cases, says Koch, they can usually make the patient noncontagious within...
...applied directly to the skin to deal with acne pustules. In tests, they treated 80 youngsters with moderate acne with four widely used antibiotics, applying the medications twice daily for eight weeks and counting the number of lesions at the end of each month. Three of the drugs-chloramphenicol, isoniazid and tetracycline-proved of little value. The fourth, erythromycin, showed that it may be worth further study. After four weeks, the drug had produced a small, but measurable reduction in acne lesions on the foreheads and cheeks of 16 of the 20 patients using...
...common drug reactions involves isoniazid, the most widely used drug against tuberculosis. One of the rarer reactions is found among victims of porphyria (see following story), who suffer acute attacks if they take barbiturates; they may also be sensitive to the sulfas. At the opposite end of the reaction scale, some victims of an unusual form of rickets need more than 1,000 times the normal quantity of vitamin D before they respond...
Even the most universally useful anti-TB drug, isoniazid, is harmless only if the patient's enzyme system can break it down readily: if not, he is likely to develop a generalized neuritis, or even an acute form of rheumatism...
...children would get the same medical and dental examinations as city youngsters. Now there are clinics for pregnant women and for well babies-along with proper care for the sick. Where TB patients once languished for lack of treatment in a sanatorium, health workers now give out supplies of isoniazid to be taken at home, and then they check to make sure the pills are really taken...