Word: isoniazids
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Dates: during 1952-1952
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...soon as they knew that isoniazid was safe, the Cornell researchers turned to the Navajos of Arizona to give it a thorough test. With their high susceptibility to TB and wretched living standards, the Indians provide a tragically large number of miliary and meningeal cases. Often, one patient has both forms. The Navajos were eager to help medical research fight the white man's disease which has killed more of them than white man's bullets ever did. Their Tribal Council put up $10,000 toward the project...
Hungry for the Bottle. The first Navajo to be treated with isoniazid was a seven-month-old baby girl named Patty. When her parents brought her to Dr. Charles M. Clark at Western Navajo Hospital in Tuba City, Patty was a wizened starveling of 9 lbs., with miliary TB. Her temperature was 103° and she had to be fed by tube. After 17 days of treatment with isoniazid, her temperature dropped to normal and she began taking the bottle hungrily. Now Patty weighs 16 lbs. and her TB seems to have been arrested...
...year-old Navajo girl named Jean Smith was Dr. Clark's next miliary case. She weighed 79 lbs., had an agonizing, rattling cough and had trouble breathing. Moreover, says Dr. Clark, the X ray of her lungs "looked like a snowstorm." Under treatment with isoniazid she soon got rid of her fever, cough and shortness of breath. Jean has eaten...
...early results in tuberculous meningitis. Dr. Clark has treated several cases which had relapsed after courses of streptomycin. After 80 days of streptomycin, eight-year-old Elsie still had a fever; she had TB germs in her spinal fluid; she was mentally clouded and suffering spasms. Within a month, isoniazid changed all that, and not long after, Dr. Clark was able to take Elsie to the circus...
Another patient who went to the circus instead of a cemetery is Little Joe, also eight. Within ten days, isoniazid ended his unbearable headache and loosened his stiff spine and neck. Now Little Joe is the life of the men's ward at Winslow Indian Sanatorium, first up in the morning and (complain the tired oldsters) the last to turn in at night...