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...freckles are utterly disarming. She enhances their effect by wearing her hair in a girlish bob. Her round brown eyes seem to be perpetually widened in astonishment at the inventiveness that people lavish on wicked enterprises. In short, Ryoko Itakura (Nobuko Miyamoto) does not fit anyone's image of a tax collector. But in her case, appearances are usefully deceptive. They camouflage a spirit demonically dedicated to exposing the cheating heart of the all-too-typical taxpayer...

Author: /time Magazine | Title: Cinema: Driven by Uncontrollable Passions A TAXING WOMAN | 5/16/1988 | See Source »

...California groups, led by Howard Goodman and Bill Ruggers, inserted the insulin gene already in bacteria last year but they have been unsuccessful in getting the E. coli to read it, according to Gilbert. The other West Coast project, run by Genentech Inc. and an organic chemist, Dr. Keiichi Itakura, announced in September that it had successfully produced human insulin using E. coli bacteria...

Author: By Daniel Gil, | Title: A Scientific Race: Recombining DNA | 11/14/1978 | See Source »

...Itakura and his associates reported that, "Artificial genes that 'command' laboratory bacteria to manufacture human insulin have been synthesized." Rather than using natural animal genes for insulin, this group built an artificial copy of the human insulin gene in two short segments and inserted these separately into E. coli plasmids...

Author: By Daniel Gil, | Title: A Scientific Race: Recombining DNA | 11/14/1978 | See Source »

...successful work was a joint effort of two five-man research teams-one at the City of Hope National Medical Center in the Los Angeles suburb of Duarte, under Dr. Keiichi Itakura, the other led by Biochemist David Goeddell at a small South San Francisco biochemical firm, Genentech Inc. Though scientists had already produced a precursor of rat insulin with bacteria, making the finished human variety posed greater difficulties. For it consists of two distinct molecular chains, a so-called A strand and a B strand, each of which is produced separately inside the cells of the pancreas under...

Author: /time Magazine | Title: Science: Creating Insulin | 9/18/1978 | See Source »

Whenever he could spare the money, which was seldom enough, Yonosuke Itakura, a poverty-stricken job printer, sent his sickly daughter Yoko from Tokyo to the hot springs in the Buddhist Temple of the Understanding Way in the mountains of Hakone. There, one day last summer, a landslide roared down the mountains burying the child, her mother and eight others beneath a varicolored rubble of clay, pumice, granite boulders and choking volcanic ash. Rescue workers searched among the debris for bodies, but before the remains of Yoko and her mother were found, the search was abandoned. Yonosuke and his sons...

Author: /time Magazine | Title: JAPAN: The Search | 10/12/1953 | See Source »

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