Word: jackpots
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Dates: during 2000-2009
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...surfer-heist movie. She loves to locate affinities in people with opposite agendas, and vice versa; so James is often isolated from his comrades, while he gets into recklessly close contact with the Iraqis. Bigelow is also a whiz at discovering fresh talent, and in Renner she hit the jackpot. The actor is ordinary-looking, pudgy-faced, quiet; can he carry a big film? Oh, yes. He soon reveals the strength, confidence and unpredictability of a young Russell Crowe...
...entertaining while our Khmer captain steered with his foot and drank an Angkor beer. The first two hours took us south past islands dotted with stilted fishing villages painted in blues and greens and oranges, then through a mangrove forest, into the Gulf of Thailand. There we hit the jackpot: a school of dolphins jumping in the waves...
...rite that is like a Mafia bar mitzvah ("Now you are a man"); a middle-management toughie who, like Tony Soprano, is in the waste-disposal business (the Camorra holds a monopoly in this industry); and two punks who quote the Pacino Scarface and think they've hit the jackpot when they stumble on a weapons stash. ("Let's rack up corpses," one says. "No use feeling depressed.") Above these scarred, drugged-out creatures are their bosses, wealthy mobsters who are still middle management in the giant organization. And to the side, but never out of firing range, nonviolent types...
...reviews on our site per story, from users who love to review," Petty said. The prize-winning stories receive far more reviews than that, and the number of positive reviews decides each story's ranking. In January, the best-reviewed story of 2008 will claim the $250,000 jackpot...
Those are odds most of corporate America would blanch at. But for drugmakers, high-priced gambles have long been the reality of research and development. To be sure, when they do hit the jackpot, the payoff can be enormous: Roche's pharmaceutical division alone raked in more than $30 billion in sales last year. Its total sales reached $43 billion, generating profits of $10.5 billion. Nonetheless, the days of this trial-and-error approach may soon be over. All of Big Pharma is feeling pressure--from Wall Street, regulators and customers--to take a smarter path to discovery for that...