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...role of propofol in Jackson's final days looms large even as the coroner's report remains under official seal. On Aug. 24, the Los Angeles Times reported that the L.A. County Coroner's Office found fatal amounts of the powerful anesthetic (also known as Diprivan) in Jackson's body. The information was contained in a search warrant for the office of Jackson's personal physician Dr. Conrad Murray that was unsealed in Houston, where Murray has an office. According to the Times, Murray told police that he had been administering 50 milligrams of propofol to Jackson intravenously every night...

Author: /time Magazine | Title: Jackson's Death: How Dangerous Is Propofol? | 8/25/2009 | See Source »

With the wisdom of hindsight, Deepak Chopra recalls a conversation he had with Michael Jackson a few years ago. "He said there's something you can take that takes you to the valley of death and then takes you back," the best-selling author and physician tells TIME. "I hadn't the vaguest idea of what he was talking about. And then he quickly changed the subject." Now, says Chopra, "I see he was talking about propofol...

Author: /time Magazine | Title: Jackson's Death: How Dangerous Is Propofol? | 8/25/2009 | See Source »

...Associated Press also reported that the coroner's office had ruled Jackson's death a homicide, raising the likelihood that one or more of Jackson's doctors may face charges. Murray is reportedly the subject of an LAPD manslaughter investigation. (How culpable are Jackson's doctors...

Author: /time Magazine | Title: Jackson's Death: How Dangerous Is Propofol? | 8/25/2009 | See Source »

...Jackson's death on June 25 has brought the subject of propofol abuse from obscure medical research papers to the celebrity-laden Web pages of TMZ. Until Jackson's death, there was little talk about it in celebrity circles. "I didn't know much about it," says Chopra. Dr. Drew Pinsky, host of Celebrity Rehab, says he had never seen the drug abused by his hard-living Hollywood clientele. Home use of Diprivan "is something I had never heard of," Pinsky tells TIME. "I'd have an easier time believing that Martians had set down outside this building...

Author: /time Magazine | Title: Jackson's Death: How Dangerous Is Propofol? | 8/25/2009 | See Source »

...benefits in the operating room but poses major risks for abusers. "In the right hands, the drug is the most effective, safest anesthetic that many of us use," says Wischmeyer. "In the wrong hands, it's a very lethal drug." (See TIME's video "A Musical Appreciation of Michael Jackson...

Author: /time Magazine | Title: Jackson's Death: How Dangerous Is Propofol? | 8/25/2009 | See Source »

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