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What Seiden and others claim is that the FDA glossed over evidence that both Redux and the older drug fenfluramine cause significant brain damage in laboratory animals, from mice to baboons. The problem, they say, is that after the drugs are withdrawn, serotonin levels plummet and stay low for weeks...

Author: /time Magazine | Title: THE NEW MIRACLE DRUG? | 9/23/1996 | See Source »

The advisory committee's recommendation wasn't legally binding on FDA Commissioner David Kessler. Last December 22 neuroscientists, including Seiden and Dr. George Ricaurte of Johns Hopkins, asked the FDA to "forgo a final decision on dexfenfluramine until more information is available on its serotonin-neurotoxic potential in humans." Nevertheless...

Author: /time Magazine | Title: THE NEW MIRACLE DRUG? | 9/23/1996 | See Source »

The cautious optimism that has begun to surface at major cancer-treatment centers is not grounded in any hard calculus. Despite some gains, cancer death rates remain unacceptably high (see chart), and the disease will kill 554,740 people in the U.S. this year. Rather, the optimism stems from an...

Author: /time Magazine | Title: THE ENEMY WITHIN | 9/18/1996 | See Source »

With a presidential campaign in full swing, the American flag may be the most pervasive symbol of the season. As a work of graphic design, it may also be the most taken for granted. This wasn't so back in the 1950s when Jasper Johns altered the course of American...

Author: /time Magazine | Title: FALL PREVIEW | 9/9/1996 | See Source »

What changed was the perception of sex offenders as compulsive recidivists. For years, Larry Don McQuay begged the state of Texas to castrate him, saying he had molested some 200 children and would resume when released from prison. Experts like Fred Berlin, founder of the Sexual Disorders Clinic at Johns...

Author: /time Magazine | Title: A CHEAP SHOT AT PEDOPHILIA? | 9/9/1996 | See Source »

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