Word: johnson
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...John Johnson, Stuyvesant PA: "Not really crazy about Tommy Thompson...
...opened some 200 franchises since 1999. The company rang up more than $100 million in sales in 2006 and plans to open 35 additional stores this year. Winmark collects a 4% royalty fee from each store; a franchise costs $225,000 on average. The formula seems to work. Steve Johnson, who owns three stores in the Midwest, says he grosses $700,000 to $900,000 annually at each and nets...
...film is outside it. Journalists are imperiled as never before; the number of reporters killed in action has reached dreadful heights, as the war zone is expanded from the old-time battlefields to nearly any location where a newsman and an Islamo-fascist might collide. (The BBC's Alan Johnson, missing for seven weeks, is only the latest kidnap victim of Muslim extremists.) Killing the messenger has become a major mission, a prime sport, among the politically and religiously deranged...
...taken ingenuity. In patients like Robert Johnson, Ali delivers the functional gene using a virus that's been modified so it won't attack the eye or reproduce. The two trial subjects so far have not had severe immune responses to the new matter in their eyes - always a danger. Scientists are especially hopeful because the procedure worked so well in its animal trials. Scanning the eyes of dogs that underwent the procedure, researchers could see how the photoreceptor cells had changed. More important, the previously blind dogs could see well enough to navigate through a maze...
...Boatright and his colleagues are working on a technique that would let ophthalmologists fix genes that not just fail to express themselves, like Robert Johnson's, but that have mutated in a way that they express themselves abnormally, a trickier proposition because doctors need to add something and suppress something else at the same time. (Boatright and co. would inject short DNA strands that, where they bound with the patient's DNA at the point of the fault, would alert the body's existing repair mechanisms to the problem). The future looks bright indeed...