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...later and accounts for 90% of Alzheimer's cases in the U.S. Two of the genes are known to interact with the amyloid-protein plaques that build up in the brain of Alzheimer's patients and eventually cause nerve-cell death and cognitive problems. The third affects the junction of nerve cells, where various neurochemicals work to relay signals from one nerve cell to another. It's not clear yet exactly how the genes increase Alzheimer's risk - in fact, most healthy people have some version of the three genes - but researchers hope that the growing pool of genetic factors...

Author: /time Magazine | Title: TIME's Top 10 Medical Breakthroughs of 2009 | 12/8/2009 | See Source »

White River Junction...

Author: By Paul Keane | Title: LETTERS: Racial Profiling at Yale | 9/16/2009 | See Source »

...other hand, the discovery of PICALM came as a bit of a surprise. That gene's activity affects the junction between nerve cells, where various neurochemicals work to relay signals from one nerve cell to another. While most of the research attention in Alzheimer's has been on the build up of amyloid protein and tau tangles that strangle nerve function, the identification of PICALM suggests that some part of the disease may have to do with a breakdown in nerve-cell communication at the junctures. "If you had given people a list of genes and said which ones were...

Author: /time Magazine | Title: Breakthrough Discoveries of Alzheimer's Genes | 9/7/2009 | See Source »

...only way. "The public option, whether we have it or we don't have it, is not the entirety of health-care reform," Obama said at a town-hall meeting on Aug. 15 in Grand Junction, Colo. "This is just one sliver of it, one aspect...

Author: /time Magazine | Title: Health-Care Reform: Obama Finesses the Public Plan | 8/17/2009 | See Source »

...camera operators. Trailed by two black suburbans, the blue-and-white jet moved east, then turned west, into the prevailing winds, throttled to full power and lifted the Obama's into the mountain sky and off to another working-vacation destination, the next town hall meeting in Grand Junction, Colorado...

Author: /time Magazine | Title: The Obamas: Stopping Traffic in Yellowstone | 8/16/2009 | See Source »

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