Word: kaplowitz
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...Paul Kaplowitz, a pediatric endocrinologist with the Virginia Commonwealth University School of Medicine in Richmond, Va., explains, "We've known for a long time that very overweight girls tend to mature earlier, and very thin girls, such as anorexics, tend to mature later than normal. We think mildly overweight girls may be maturing early as well." Kaplowitz emphasizes that the correlation is merely statistical; not every girl with a little extra baby fat will develop breasts early...
Exactly why obesity and early development should be linked is not well understood. But Kaplowitz suspects early breast development may be encouraged by a protein called leptin. "We know that fat cells produce leptin," he says. "And leptin is necessary for the progression of puberty." Another clue, according to Duke's Freemark, is that overweight girls have more insulin circulating in their blood. Says Freemark: "Those higher levels of insulin appear to stimulate the production of sex hormones from the ovary and the adrenal gland...
...these factors--doctors say early development has become too widespread to be treated as a medical aberration. In the past, girls who developed breasts before age 8 were often given hormone therapy to slow things down. But in a report being prepared for the Pediatric Endocrine Society, Kaplowitz and co-author Dr. Sharon Oberfield of Columbia University argue that most girls between 6 and 8 who develop breasts or pubic hair should be reclassified as normal and left untreated. "Three-, four- and five-year-old girls should still be managed aggressively," he says, "but there are far fewer of these...
According to students Richard Goldstein and Lori Kaplowitz '85, the hour-long morning tutorial is only the start of a schedule that each day includes lectures, labs, and afternoon sessions in clinical care. Somewhere between case studies, lab benches, and figuring out how to give a physical; students must find time to independently research the problems they raised in the tutorial session...
...sprinting corps, one of the Bruin's strengths, is led by Jan Kaplowitz. "We are really a yoong team," Commons said, "but our sprinters and freestylers are our strong points...