Word: kaposi
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...chlamydia, a common but curable venereal disease. Doctors prescribed several antibiotics and put him on a low-salt diet. Nothing worked. His muscles wasted away, and his lungs filled with fluid. Robert R. died on May 15, 1969. An autopsy revealed the distinctive purplish lesions of AIDS- related Kaposi's sarcoma...
...says Author Randy Shilts, was Gaetan Dugas, a handsome blond steward for Air Canada, who used to survey the men on offer in gay bars and announce with satisfaction, "I'm the prettiest one." Using airline passes, he traveled extensively and picked up men wherever he went. Dugas developed Kaposi's sarcoma, a form of skin cancer common to AIDS victims, in June 1980, before the epidemic had been perceived by physicians. Told later he was endangering anyone he slept with, Dugas unrepentantly carried on -- by his estimate, with 250 partners a year -- until his death in March 1984, adding...
Interferon's performance against other forms of cancer has been inconsistent, but when it does work, the results can be dramatic. It has produced complete remissions (though not necessarily permanent cures) in advanced cases of kidney cancer; in malignant melanoma, a lethal form of skin cancer; and in Kaposi's sarcoma, a skin cancer that often strikes AIDS victims. In one study reported in Houston, just five out of 52 patients with advanced melanoma were successfully treated with interferon. But this handful was extraordinary: all signs of cancer disappeared within four months, even though the disease had spread to such...
...Haitian connection is still puzzling. The disease apparently broke out on the impoverished Caribbean isle in 1981, at about the same time as it did in the U.S. Some experts suspect that AIDS is caused by a newly introduced viral agent from Africa, where Kaposi's is common, and may have been transmitted by Haitians who once worked in Zaïre. Port-au-Prince has many popular gay bars, and the disease could have been brought back to the U.S. by visiting Americans?or taken to Haiti by Americans in the first place. Recent investigations suggest that the disease...
...cure is in sight. But the research already has benefited some patients. New knowledge about the immune system has inspired doctors to be more careful when treating Kaposi's to use therapies that do not lead to further suppression of the immune system. Fauci of NIH has conducted a bone marrow transplant that bolsters a patient's immune system. Along with many other researchers, he is testing the effects on AIDS patients of new forms of interferon, a component of the human immune system that can now be reproduced by genetic engineering...