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...nearly 65 hours, an artificial heart beat within Haskell Karp's chest. Then, 30 hours after the 8-oz. plastic device was replaced by the heart of a 40-year-old woman, Karp died last week in Houston's St. Luke's Episcopal Hospital, succumbing to pneumonia and kidney failure. By becoming the first human recipient of a completely artificial heart, Karp had briefly raised all sorts of expectations the world over. His death immediately touched off an angry controversy over the wisdom of trying out the device without further experimentation. It also brought into the open...

Author: /time Magazine | Title: Transplants: An Act of Desperation | 4/18/1969 | See Source »

...desperate moments began even before the controversial heart started pumping life back into Karp, 47, a printing estimator from Skokie, 111. Cooley warned Karp that if his badly damaged heart proved to be beyond repair, it might become necessary to use the experimental plastic device. Because the artificial heart is believed to cause serious damage to the blood if left in the body for too long, Cooley, along with Karp's family, issued a nationwide appeal for a human heart to replace it as quickly as possible. It was a starkly explicit appeal,calling for a person "with irreversible...

Author: /time Magazine | Title: Transplants: An Act of Desperation | 4/18/1969 | See Source »

Source of Power. Standing by was Argentine-born Dr. Domingo Liotta of the Baylor College of Medicine, who has worked on artificial hearts for ten years. He now had ready a device that might keep Karp alive for a week or two. It is about the same size as a natural heart and is made of Silastic (a silicone plastic), with Dacron cuffs for attachment to the "distributor cap," or blood-vessel connections, in the remnant of Karp's own heart. It is self-contained except for one essential ingredient: a power system to deliver a steady, pumping beat...

Author: /time Magazine | Title: Transplants: An Artificial Heart | 4/11/1969 | See Source »

With the artificial heart in place, Cooley led these tubes out through the cut in Karp's chest wall. The heart-lung machine was switched off and the console switched on. At a slow-normal heart rate, the pump alternately sent a volume of carbon dioxide under pressure into sacs in the artificial heart to force blood out of the ventricles to the lungs and the rest of the body, then relaxed this pressure to let the heart refill with blood...

Author: /time Magazine | Title: Transplants: An Artificial Heart | 4/11/1969 | See Source »

...Karp soon regained consciousness and obeyed commands to move his hands and wiggle his toes. Next morning, with a breathing tube removed from his throat, he said a few words. His wife Shirley issued an appeal for a heart donor. At week's end, though no donor was yet in sight, Karp was holding up well and Surgeon Cooley was standing by, eager to remove the artificial device and replace it with a natural heart...

Author: /time Magazine | Title: Transplants: An Artificial Heart | 4/11/1969 | See Source »

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