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...drugs infringe on a patent they were jointly awarded in 2002. The trial began April 10 in U.S. District Court for the District of Massachusetts. Closing arguments are scheduled to take place tomorrow. The patent covers methods of treating diseases by modulating the activity of the molecule NF-kB, a “transcription factor” involved in protein production. Scientists from Harvard, MIT, and the Whitehead Institute discovered these methods in the 1980s, and the institutions licensed the patent exclusively to Cambridge-based Ariad. The four parties filed suit against Eli Lilly on the same day the patent...
...mile-long park replacing wharves. Nearby, developer Pres Kabacoff's $318 million plan to transform the St. Thomas housing project into River Garden-a mixed-income neighborhood with Creole cottages, Victorian doubles and Greek Revival houses-should get back on track this month. And a few blocks away, KB Home, one of the nation's largest builders, will turn dirt this spring on 58 lots for Orleans-style homes. With $50 billion in private insurance payouts and government help on its way to the region, Mayor Ray Nagin is predicting an "explosion of growth," especially downtown...
...else the hurricane may produce is what Nagin predicts will be "the biggest construction boom this country has ever had." While the poorer districts may be languishing, in some areas there are signs the boom may be happening. Deals are popping up around downtown and along the Mississippi riverfront. KB Home, one of the nation's largest home builders, is racing to start up to 10,000 Orleans-style houses just across the parish line, as well as 58 lots downtown. Bruce Karatz, CEO of California-based KB Home, promises that the houses "will have the New Orleans feel...
...KB Toys, Sports Authority and Staples are some of the dozen or so retailers to outsource that job to the Return Exchange, a California company whose software automatically tells cashiers to bounce customers who bring back items too often. Exactly what "too often" means varies by retailer, the company says...
...runaway smash alone would not solve the woes of the toy business. Toy stores see little Christmas cheer in tackling the big-box discounters Target and Wal-Mart, and many are shutting down. Since last season's brutal price war--led by Wal-Mart--KB Toys and FAO Schwarz have closed roughly 600 stores between them. Toys are increasingly merchandised as impulse items at drugstores, supermarkets and even coffee shops. Starbucks has sold loads of the Cranium board game. KB, operating under bankruptcy protection, says it will close 164 of its remaining 820 stores in January. FAO now consists...