Word: keying
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...malfunction affecting one of these genes is not, in itself, enough to cause autism, the Icelandic researcher is quick to point out. It would take a combination of several genetic flaws and perhaps environmental factors as well for autism to emerge. "This gene is a key driver in causing autism in about 15% of cases," Harkonarson asserts...
...specific kind of genetic change: deletions and duplications of genes. While there are many such changes associated with autism, most are very rare. This paper, however, found an intriguing pattern among two genes already linked to autism and nine newly identified targets. Most play a role in two key systems in the brain. One is the same brain-wiring system - neural cell adhesion - implicated in the first paper. The second is a set of housekeeping proteins - the ubiquitin system - that whisk away old brain connections and set the stage for new ones...
...Charles has been a key resource to Harvard’s outdoors community—hosting boat races including the Head of the Charles Regatta, and the annual Polar Bear Swim, an annual event in which Alaska Klub members jump into the river despite Cambridge’s freezing winter temperatures...
...While the conflict has always been something of a low-intensity guerrilla war, recent news reports from the region confirm that Taliban militants have begun to advance into a key region just 60 miles from Pakistan’s capital, Islamabad. A temporary peace agreement has stopped the worst of the fighting, but the insurgency is clearly an existential threat to the Pakistani government, which has been relatively cooperative with the U.S. to root out terrorists in the region. As such, given the critical security situation in Pakistan and the region as a whole—Islamabad also controls...
...region's old-school political regimes. Now, of course, the Republican Party is struggling to move beyond its base of rural Southern white Protestants and into the Midwest and Northeast. So the governor's races quickly taking shape in Virginia, South Carolina, Georgia and in Alabama will be key tests of whether the Democrats can extend their recent gains. (Watch a video where Artur Davis and others discuss who should be TIME's 2008 Person of the Year...