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...More Gentle Way Thalidomide works in three ways to fight cancer: it prevents the formation of new blood vessels that feed tumors, reduces inflammation and kick starts the body's immune system. While existing anticancer agents kill off lymphocytes and white blood cells, which control immune and inflammatory responses, thalidomide has no toxic effect on them. It is also a potent inhibitor of cell movement, thus preventing inflammation around a tumor. Though thalidomide does have side effects, like dizziness and tingling in the toes, it is more gentle than existing therapies...
...Agnelli style. Gianluca Pediconi, an analyst at Credit Suisse First Boston in Milan, says the automaker will need a major reshaping of its product line and improvement of brand image after a decade of missing the market. And Agnelli's death does nothing to ensure a kick start. "The emotional impact is strong," says Pediconi. "But it's hard to think his death will accelerate any major change in the short term. What's needed are new products, and from frozen design to launch takes at least 30 months." In the meantime, two family heirs - from distant generations - will carry...
...stock market is levitating and unemployment is falling around election time, 21 months from now, when most of the benefits will start to kick in, Republicans believe that key voting groups like married couples and seniors will not really care if the rich got richer as long as they did too. "Our first challenge is to allow Americans to keep more of their money so they can spend and save and invest," Bush said in announcing the program in Chicago last Tuesday...
Norman Cousins would have got a kick out of this week's issue. He was the former editor of the Saturday Review who, when struck with a debilitating connective-tissue disorder, checked himself out of the hospital and into a hotel room, where he medicated himself with megadoses of vitamin C and endless reruns of Marx Brothers movies and old episodes of Candid Camera--anything that would keep him laughing and relieve his pain. It worked, according to the account he wrote up for the New England Journal of Medicine and later published as a book, Anatomy of an Illness...
...fourth quarter. Neither France nor Italy, the euro zone's second- and third-largest markets respectively, looks likely to have done much better, with 2002 growth estimated at 1% and .4% respectively. And this year? The German Institute for Economic Research estimates 2003 growth will be .6%, possibly kicking off with an economic contraction in this quarter - technically, that would be a recession if the previous quarter turns out to be negative too. Recession or not, the growth figure is well down from Economy and Labor Minister Wolfgang Clement's forecast last autumn of 1.5%. Even the good news...