Word: kleine
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Dates: during 1960-1969
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Familiar But Unfamiliar. The two types of cancer involved are called basal-cell and squamous-cell carcinomas, from the types of skin cells among which they are found. For patients who had widespread forms of either of these cancers, Dermatologist Edmund Klein of the Roswell Park Memorial Institute in Buffalo tried using familiar anticancer chemicals-but he used them in an unfamiliar manner...
...Klein figured that with localized application he could keep the drugs out of the bloodstream and use them on skin cancers without any of the dangerous side effects. Cautiously, he injected minute doses between layers of the skin, or applied the drugs in ointments and creams. From the beginning, he got an encouraging and prompt response. Furthermore, a number of the drugs he was testing seemed to sensitize the patients' skin, particularly in the cancerous areas. Subsequent applications then caused a bright red, allergic-type reaction. As the dosage was repeated, the reaction got stronger, and selectively destroyed cancer...
Clue to Prevention. The inflammatory reaction after a sensitizing dose is so strong, Dr. Klein told the Medical Society of the State of New York, that it even shows up cancers too minute to be detected by other means. Thus it makes prevention possible by revealing places where precancerous cell changes have just begun. The basis for this effect is not yet understood, but it is being investigated at other cancer centers where the treatment is being tested...
...Composer Stevens, is "a bit of a revolting phrase," but accurate nonetheless. The band helps project the same image by dressing up in old-timey clothes ("early bad taste") and lolling around the stage like lazy good-for-nothing aristocrats. To make the point, one of the members, Alan Klein, has taken on the title of Tristram, the seventh Earl of Cricklewood...
...forward play of Steve Klein, Bruce DeTora, Ben Phinney, Bill Bellows, and Browne was largely responsible for the offensive play in the second half. Harvard came close to scoring on many plays besides the two goals...