Word: knudson
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Certain types of cancer seem to run in some families, and in the early 1970s a geneticist named Alfred Knudson came up with one explanation: genes that normally protect against the cancer somehow get lost or damaged. Other scientists suggested that these genes serve as "off" switches, restraining cells from replicating ceaselessly and forming malignancies. If the switches are not inherited or are somehow disabled by, say, radiation, chemicals or viruses, cancerous growth might start. Logical enough; but as years passed without hard evidence, people questioned whether such genes existed...
Last week brought vindication for Knudson, now at Philadelphia's Fox Chase Cancer Center. A group of Boston-area scientists announced that they had discovered a gene that normally blocks retinoblastoma, a rare and often hereditary eye cancer that develops in children. The find should lead to an accurate test for genetic susceptibility to the disease and perhaps improved treatment. It has also raised hopes that other genes will soon be found that inhibit the more common cancers of the lung, breast and colon...
...GOLF CLASSIC (CBS, 4-5 p.m.). Harold Henning and George Knudson play George Archer and Bob Lunn in the first of a 14-round elimination match for $225,000 at the Firestone Country Club in Akron, Ohio...
...green of the par-four twelfth hole-360 yds. away. Jack's first round score was a two-under-par 70; he followed that with a 68 and a 69, at week's end had moved into a tie for the lead with Canada's George Knudson...
...Canada Cup, emblematic of world golf supremacy, for the eighth time in 14 years, as Jack Nicklaus and Arnold Palmer shot a combined 72-hole score of 548, or 28 under par; at the Yomiuri Country Club, in Tokyo. The individual competition was won by George Knudson, who sank a 12-ft. putt on the second hole of a sudden-death play-off to break a tie with Japan's Hideyo Sugimoto. Nicklaus finished third, Palmer fifth...