Word: kr
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Dates: during 1940-1949
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...KR Progress. The most hopeful Russian lead is the KR treatment developed by the University of Moscow's Dr. Grigori Roskin and wife Nina Klyueva (TIME, July 8). Roskin and Klyueva reported that it had been tested on 18 "incurable" cancer patients, had destroyed tumors in eleven...
...KR (for its discoverers' initials) is derived from Schizatrypanum cruzi, a South American trypanosome that has an affinity for cancer cells. When injected into cancerous mice, it gradually dissolves their tumors, but also kills the mice. Roskin & Klyueva developed a toxin from killed trypanosomes that dissolved cancer cells but was harmless to healthy cells. The cancer-destroying element, they concluded, was not the trypanosome itself but a toxin which it secreted. The toxin has proved safe for human patients...
...lead, the two Russian researchers tried other toxins. Two-diphtheria and tetanus-seemed to work. Tested on cancerous mice, tetanus toxin checked or reduced tumors in half the cases. Diphtheria toxin did even better: out of 65 mice with cancers, it cured 39, stopped tumor growth in 19. Unlike KR, the toxins have still to be tested on humans. U.S. researchers, fascinated but uncertain, are pursuing experiments along similar lines...
...called immigration of the 40,000 Turks of Armenian origin, there can be no more significant answer than repeating a statement of our former Premier Sükrü Saracoglu...
...very limited supply of KR has permitted, clinical tests have also been made on human cancers (i.e., where the growths were not so large that their dissolution would cause malfunctions). One inoperable throat cancer, Drs. Roskin & Kluyeva report, disappeared in two weeks. In an unspecified number of other cases KR "reduced" or partially destroyed cancer. But a lot more evidence is needed, the doctors admit, before the usefulness of KR can be safely evaluated...