Word: krebiozen
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There were two secrets about Krebiozen: What is in it? And does it work? Yugoslav Emigre Dr. Stevan Durovic, who says he extracted the so-called anti-cancer drug from horse serum and brought it from Argentina to Illinois, has never identified the drug's ingredients, and both private and Government cancer experts for years refused to give the unknown substance wide trials with patients. Last week the first secret was out: the Food and Drug Administration stated flatly that Krebiozen is nothing more than the common amino acid derivative, creatine, found naturally in the muscle tissue...
...Durovic surrendered a sampling of Krebiozen to FDA agents last July, and at once chemists began systematic analysis with an infrared spectroscope. After the complex spectrogram was compared with that of thousands of other organic compounds, the pattern of Krebiozen was found to match that of creatine. Ironically, Krebiozen is much easier to produce than Dr. Durovic may realize; he uses benzene, in which creatine is highly insoluble, for extraction. Using plain water as a solvent for the process, he might get several hundred times more amino acid derivative from each horse...
Observing the FDA investigation were researchers from the National Bureau of Standards, the National Cancer Institute, and four universities. Even with such impeccable scientific credentials, the report is not likely to go uncontested. Krebiozen has strong emotional appeal and powerful political supporters (among them, Illinois' Senator Paul Douglas), and one of its most passionate promoters, Physiologist Andrew Conway Ivy, stubbornly insists that "creatine isn't Krebiozen. We're going ahead as in the past." But before long, the other secret of Krebiozen may be found: the National Cancer Institute is scrutinizing the records of 507 patients treated...
...June 7, a tough provision of last fall's Drug Amendments Act became effective. To continue interstate dealings in Krebiozen, Dr. Durovic had to file with FDA a detailed plan for his investigation. He did so reluctantly, at the last minute. Then last week, just as FDA was concluding that his plan was "grossly inadequate," Durovic abruptly withdrew his proposal, angrily charging bad faith on the part of the Government. The Department of Health, Education and Welfare responded: "Your action automatically makes illegal the continued interstate delivery of the product." Dr. Ivy defiantly announced that he would continue...
...Krebiozen's backers have powerful friends on Capitol Hill; last week resolutions were introduced in both houses of Congress to require the Government to give the controversial drug another chance...