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...body's own immune system often attacks the anti-sense DNA, mistaking it as a potentially harmful virus. For another, many cells in the body don't allow the anti-sense molecules to cross their membranes. "Nine years ago, everyone thought, wow, this is dynamite," says Dr. Art Krieg, editor of the journal Anti-Sense and Nucleic Acid Drug Development. "Then they ran into technical hurdles, and the pendulum swung the other way." Now, says Krieg, a few anti-sense compounds are starting to show promise. Among them is a drug called Vitravene, which was approved by the Food...

Author: /time Magazine | Title: Drugs By Design | 1/11/1999 | See Source »

Madden says the long learning curve explains why so many grayhairs who should be regaling bowling buddies with stories about the good old days are still putting on helmets. The league will have three quarterbacks in their 40s as of next week, when Tennessee backup Dave Krieg enters middle age. Seattle Seahawks starter Warren Moon is 41, and Atlanta Falcons backup Steve DeBerg, at 44, is the age of Manning and Leaf combined. Oakland Raider backup Wade Wilson is 39; Denver Bronco John Elway, 38; and Minnesota's Randall Cunningham, 35, came out of retirement two years ago and threw...

Author: /time Magazine | Title: Rookies Under Siege | 10/19/1998 | See Source »

Part of a journalist's training must be to keep a straight face while interviewing a character like Milosevic. WILLIAM J. KRIEG Fairport, New York...

Author: /time Magazine | Title: Letters, Aug. 7, 1995 | 8/7/1995 | See Source »

Despite nursing a shoulder bruise, Dave Krieg passed for two touch-downs--to tight end Dan Ross for 11 yards and Steve Largent for 17 yards. The Seahawks' other touchdown came on a 5-yard run by Curt Warner in the second quarter...

Author: NO WRITER ATTRIBUTED | Title: Pro Football Weekend Roundup | 12/2/1985 | See Source »

...company's salaries and perks are widely regarded as among the most attractive in the industry. New employees are expected to spend their working lives with the firm, and regularly go through intensive training programs to upgrade their skills. "We hire with a career in mind," says Edward Krieg, director of management development. Although some overseas IBM plants are unionized, the firm has never had a union vote in any U.S. facility...

Author: /time Magazine | Title: The Colossus That Works | 7/11/1983 | See Source »

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