Word: kriegstein
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Dates: during 2000-2009
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...Raptorex came to light, meanwhile, is a story in itself. About three years ago, Sereno, who usually does his own fossil-hunting, was approached by ophthalmologist and avid fossil collector Henry Kriegstein for help in identifying a newly purchased specimen. Kriegstein had bought the fossil legally, but when Sereno saw it, he became convinced it was from China and that it had almost certainly been smuggled out of that country. "I told him that I'd help," says Sereno, "but only if he was willing to donate the fossil to science and let us return it to China when...
...Kriegstein agreed. Sereno, in turn, gave the remarkable specimen Kriegstein's surname (in honor of his parents, Holocaust survivors who are still alive), and listed Kriegstein as a co-author on perhaps the most important paleontology paper of the year. "In the normal course of things," says Sereno, "this fossil could have ended up on someone's mantelpiece or been forgotten in an attic somewhere and lost to science. Now China gets its property back, and Dr. Kriegstein has found immortality for his family. Everybody wins...
...Arnold Kriegstein, director of the Institute for Regeneration Medicine at the University of California, San Francisco, is excited by the advance but notes that it is still relatively inefficient. "The ability to make cell lines from patients with any risk of genetic alteration is a significant step, but the efficiency of 0.001% of cells is low, and even that took two months to achieve," he says, referring to the fact that only a tiny percentage of skin cells in the study transformed into iPS cells over two months. "How readily or quickly this technology is applied, and whether the efficiency...
...just seeing the end stages." No longer. Now the major steps in the disease process will be exposed, with each one a potential target for new drugs to treat what goes wrong. "This is a sea change in our thinking about developmental biology," says Dr. Arnold Kriegstein, director of the Institute for Regeneration Medicine at the University of California, San Francisco. "I consider it a real transformative moment in medicine...
...of Bush's original order, Harvard decided to use private funding to develop about 100 new cell lines from fertility-clinic embryos, which it shares with researchers around the world. Scientists, desperate for variety, snap them up. "Not all embryonic-stem-cell lines are created equal," says Dr. Arnold Kriegstein, who runs the Institute for Regeneration Medicine at the University of California, San Francisco. "Some are more readily driven down a certain lineage, such as heart cells, while others more easily become nerve. We don't understand how it happens, but it does mean we need diversity...