Word: labs
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Dates: during 1970-1979
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Epps said that so far this year no student has been disciplined for selling drugs on campus and that Davis and Walters agree the lab-manufactured drugs are probably not synthesized at Harvard...
...report says the highest energy expenditures made by the University go for steam, used in heating and cooling, and for electricity, used to power the fans and pumps of the heating and ventilating systems, and to power lights, lab equipment, and air conditioning systems...
Like other biomedical research facilities, it experiments with rodents of all sorts, is filled with glassware of every shape and size, and has the latest scientific gadgetry. Yet there is something special about this particular lab at New York's Rockefeller University. For the past decade, its doctors, chemists and biologists have been engaged, largely unheralded, in an unusual task. They are fighting what they call "orphan diseases," a group of widely differing illnesses that have one thing in common: no one has done very much to develop drugs for them...
...fill this gap that Biochemist Anthony Cerami created the orphan-diseases lab. Unlike the drug companies, the scientists could not afford to screen thousands of compounds in hopes of finding one that might work. Instead, they concentrated on combining what was already known about a disease with their own ingenuity...
Indeed, it was brainstorming that got the lab's first project-a study of sickle-cell anemia-off to a heady start. The Rockefeller scientists realized that any treatment for this genetic disease, which affects perhaps 2 million people around the world, had to be directed at stopping the characteristic sickling, or distortion, of the red blood cells that occurs after they unload their cargo of oxygen. But how? During cocktail-party chatter, Lab Director Cerami learned from a colleague that a byproduct of urea-a chemical called cyanate-can prevent sickling. Tests on both animals and humans confirmed...