Word: labs
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Dates: during 2000-2009
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...antibodies then go through testing to make sure they will bind to cancer cells with the designated receptor, that they can be absorbed by the body and that they won't have toxic side effects. Some of these studies can be done in the lab, but they quickly move into animal and finally human subjects. Already, Millennium has 40 potential targets for monoclonal-antibody drugs against various cancers, and Tepper's goal is to generate 10 to 12 new ones each year...
...acts broadly on many tissues in the body, ACE-2 is particularly active in heart and kidney cells, where it might be more effective in controlling high blood pressure. Because they already knew on the molecular level exactly how ace worked, Tepper's team also knew precisely which lab tests would determine whether ACE-2 had the same effects...
After Columbia, Varmus bounced around different research jobs for a couple of years before landing in J. Michael Bishop's lab at the University of California at San Francisco in 1969. It was their collaborative work on the genetic basis of cancer that led to the 1989 Nobel Prize in Physiology or Medicine. (Bishop, who is now a Harvard Overseer, declined through his spokesperson to comment on a potential conflict of interest in voting to confirm his closest collaborator, which would happen if the Harvard Corporation recommended Varmus for the presidency...
...NASDAQ board meeting in Manhattan last month, a visitor approached a compact, white-haired guy who looks as if he belongs in a college chemistry lab and asked if he was thinking about a top job in the new Administration. "No way," replied Paul O'Neill, with a smile. "I'm too old." O'Neill, 65, allowed as how he might consider running a task force on something really messy and complicated, such as fixing Social Security. But having spent the past 23 years running Alcoa and International Paper, O'Neill and his wife Nancy Jo were looking to step...
...often on Ryder's mind. "Could you take a cell from a Morro Bay kangaroo rat and bring it back, and would it be the same?" he asks. "There are a lot of questions, but we don't have that option now because nobody saved the cells" while lab work was being conducted on the rodent in the 1970s. "The future will want to know about these species, and the lingua franca of biology is increasingly going to be genomic information. If nobody saves the DNA of these samples, it's going to be a very fragmented picture." There...