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...drugs the same way bacteria do: through evolution. Since organisms with drug-resistant traits are better able to withstand contact with the drugs, they survive long enough to replicate and pass their traits to the next generation. With repeated exposure, a population will become increasingly resistant, with a larger and larger proportion of the organisms showing the protective attributes. Already, U.S. health authorities recommend against using two other flu antivirals, amantadine and rimantadine (sold as Symmetrel and Flumadine, respectively), due to concerns that influenza A has become resistant. But, so far, Tamiflu resistance doesn't seem to be following...

Author: /time Magazine | Title: Drug-Resistant Flu Virus on the Rise | 1/31/2008 | See Source »

...club as Shore was out of them. She had helped many of them by lending them money, even giving some places to stay. Plus, no one wanted to antagonize the woman who was the gatekeeper for their show-biz dreams. But after Shore opened a second, larger showroom at her club, where she paid big-time headliners?but not the younger comics who also appeared there?the comedians rebelled...

Author: /time Magazine | Title: The First Comedy Strike | 1/31/2008 | See Source »

...year and 937 U.S. fatalities later, the surge is a fragile and limited success, an operation that has helped stabilize the capital and its surroundings but has yet to spark the political gains that could set the stage for a larger American withdrawal. As a result of improving security in Iraq, the war no longer is the most pressing issue in the presidential campaign, having been supplanted by the faltering U.S. economy. Voters still oppose the war by nearly 2 to 1, but Democrats sense the issue could be less galvanizing as troops begin to return home. Republicans who supported...

Author: /time Magazine | Title: The Surge At Year One | 1/31/2008 | See Source »

...questionnaires, which were sent to colleges whose endowments topped $500 million as of the end of 2007, come amid a push to force universities to spend a larger share of the endowments, which some lawmakers believe would reduce tuition costs...

Author: By Nathan C. Strauss and Kevin Zhou, CRIMSON STAFF WRITERSS | Title: Senate Examines Endowments | 1/30/2008 | See Source »

...become increasingly clear, the ideological coalition Romney so eagerly courted no longer controls the fate of the GOP, at least in the early voting states - which have favored Mike Huckabee, a populist who trumpets the occasional role of larger government, and John McCain, a legislative maverick who does not always play by the Republican rulebook. Romney tried to run as the establishment candidate, only to find that the establishment no longer held the power...

Author: /time Magazine | Title: Is Romney Fighting the Last War? | 1/30/2008 | See Source »

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