Word: late
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...Clusterin may be involved in helping to clear away the amyloid that forms in the brain; but another variant of the gene may also allow amyloid to form fibrils, the sticky protein arms that further anchor amyloid plaques to nerve cells, much like a spider web ensnares prey. In late-onset Alzheimer's, it's possible that the body cannot balance these two functions of clusterin. "It may be that the difference between a variant of clusterin that protects from Alzheimer's versus one that has a higher risk is the balance between clearing amyloid versus causing it to form...
...protein and tau tangles that strangle nerve function, the identification of PICALM suggests that some part of the disease may have to do with a breakdown in nerve-cell communication at the junctures. "If you had given people a list of genes and said which ones were involved in late onset Alzheimer's disease, PICALM would have been less likely than the others to be picked," says Goate...
...surprisingly, the scheme has accounted for more than half of all new companies founded thus far this year. "The auto-entrepreneur plan has been an impressive success, beyond what we'd been counting on," noted Hervé Novelli, secretary of state for small- and medium-size businesses, in late July...
...million oil-and-gas-exploration deal. More recently, in July, Prime Minister Gordon Brown met Gaddafi during the G-8 summit in Italy. And a week before al-Megrahi's release, John McCain led a group of fellow Senators in trade talks with Gaddafi, tweeting on Aug. 15, "Late evening with Col. Qadhafi at his 'ranch' in Libya--interesting meeting with an interesting...
...team managing only two shots on goal during the period. “Just looked slow, speed of play [was] slow—over-passing...I think it was just first game jitters,” Harvard coach Ray Leone said. Brought to life by Harvard’s late offensive awakening, the visiting squad went on the attack beginning in the 51st minute. One San Diego State shot hit the crossbar, while another went high, and a trio of corner kicks was cleared by the Crimson defense. But the fourth corner kick would be the charm, when Aztec defender...