Word: late
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...timing of Kraft's offer - initially tabled in late August but made public only Monday - makes good sense. Part way through a years-long plan to boost its margins, Cadbury has an earnings potential that looks healthy. Having spun off its troublesome drinks business in 2008, it saw its profits and margins both rise in the first half of this year. Nor is there much concern about Kraft's being able to pull off such a merger. Deals involving a large firm's acquisition of a significantly smaller one - revenues at Kraft are more than four times those of Cadbury...
...three new genes, known as clusterin, complement receptor 1 (CR1) and PICALM, were uncovered by two separate research groups, one in Wales and one in France, who linked the genes to the most common form of the memory disorder, late-onset Alzheimer's - the type that affects patients in their 60s or later and accounts for about 90% of all Alzheimer's cases. The only other gene connected with the condition, apolipoprotein E (ApoE), was identified in 1993; since, researchers have tirelessly hunted for other key genes, knowing that 60% to 80% of the progressive, incurable disease is genetically based...
...until now, three of the four known genes associated with the disease were connected to the rarer, inherited form, which appears in adults as young as 40 or 50. The three additional genes, identified in the new papers, now tip the balance of genetic understanding in favor of the late onset condition that affects a majority of the 5.3 million patients living with the disease in the U.S. (See how to prevent illness...
Based on the prevalence of the new genes and variants in the populations studied, the U.K. and French groups speculate that about 20% to 25% of late-onset Alzheimer's can be explained by ApoE; 8% to 12% by clusterin; and another 3% to 5% by CR1 and PICALM...
...politics is poker, the best players know when to double down and when to cut their losses. For Italian Prime Minister Silvio Berlusconi, a sex scandal that had dogged him for months seemed to be finally quieting by late July. Though his reputation was stained, his popularity was solid and it seemed time to put the controversy behind him and get back to trying to run the country...