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...choice with Oberst is fairly simple: laugh at him or cry with him. Laughter is certainly the path of least resistance, especially when confronted with the two hulking new Bright Eyes albums--I'm Wide Awake, It's Morning and Digital Ash in a Digital Urn--released simultaneously on Jan. 25. Over the course of 22 tracks, there is exactly one attempt at relative lightness--"I always get lost when I leave the Village/ So I couldn't come meet you in Brooklyn last night" (well, I chuckled)--and Oberst whispers it lest anyone notice. His emotional palette...

Author: /time Magazine | Title: Music: Indie Rock's Dark Prince | 1/23/2005 | See Source »

Dahiyat and his professor may have the last laugh. In 1997 they founded Xencor, with Dahiyat in charge, based on the protein-creation process called Protein Design Automation (PDA) that they had refined on the supercomputer. If all goes as planned, in about a year Xencor will start human trials of a protein that combats multiple sclerosis, rheumatoid arthritis and other diseases. Xencor has signed contracts with Genentech, Eli Lilly and other companies to develop additional drugs...

Author: /time Magazine | Title: Innovation: Tech Pioneers | 1/23/2005 | See Source »

...City's first law was that onstage its performers should avoid tension and strive for harmony. "You're supposed to make your fellow actors look good," says Ramis, also an early Second City star. "Bill internalized that ethic more than most. Belushi would come out, and the audience would laugh before he opened his mouth, but then he'd go into an extended character thing that would make the other actors feel superfluous. Bill got other people involved. He had energy, integrity. He was fascinating to watch...

Author: /time Magazine | Title: The Many Faces of Bill | 1/3/2005 | See Source »

Although humor is only a subtle part of his recent film performances, Murray still enjoys making people laugh, and he treats any kind of public appearance--a spot on Letterman, throwing out the first pitch at a Cubs game, his frequent rounds at charity golf tournaments--as a chance to recreate the spontaneous charge of Second City. "The best thing I do all year is Pebble Beach," he says. "There's 18 greens and 18 tees. That's like 36 shows--and that's just the formal rooms...

Author: /time Magazine | Title: The Many Faces of Bill | 1/3/2005 | See Source »

Sometimes when she talks about her work, Azadeh Tabazadeh mischievously mentions talk-show host Rush Limbaugh, who famously asserted that volcanoes are the cause of ozone depletion. "He was only half right," she says with a laugh. For as Tabazadeh and her colleagues have shown, volcanic eruptions do speed up the rate of ozone depletion--but only because their emissions combine with industrial pollution to create a destructive cocktail. Volcanic chlorine, for example, is water soluble, so it is quickly removed by rain. The sulfurous compounds that volcanoes spew out are another matter. These rise high into the atmosphere...

Author: /time Magazine | Title: Looking for Clues, Above and Below: THE SKY DETECTIVE | 1/2/2005 | See Source »

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