Word: ldl
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Dates: during 1990-1999
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NOTHING IS EVER SIMPLE WHEN IT COMES TO THE heart. First the big worry was a high cholesterol level. Then, it was discovered, cholesterol comes in two varieties, and the real question was whether one had more of the good type, HDL, rather than the bad kind, LDL. Now it appears that HDL itself contains a mix of both good and bad elements. What may really count in the development of heart disease, according to scientists at a meeting of the American Heart Association, is the amount of the HDL component, LpA-I. The more of this protective protein...
...greater among men with high blood levels of iron than in those with lower readings. For each 1% increase in the amount of ferritin (a protein that binds iron), the risk of heart attack increased by 4%. The reason, many doctors suspect, is that iron may interact with LDL, "the bad cholesterol," in a way that promotes the formation of plaque on arterial walls...
...fingerprints of genes that predispose us to common kinds of diseases," Hood says. Based on the genetic profile, the computer will dispense some medical advice. It might say, "This individual has a tendency toward skin cancer and should avoid overexposure to the sun." Or: "He has insufficient LDL cholesterol receptors and a proclivity to obesity, so he should begin a high-fiber, low-fat diet at age 3." Explains Mark Skolnick, a geneticist at the University of Utah: "Once you can make a profile of a person's genetic predisposition to disease, medicine will finally become largely predictive and preventive...
...among those in this group who received aspirin along with the beta carotene capsules. The Harvard researchers have begun a trial in 45,000 postmenopausal women to see if a similar effect occurs in women. Scientists speculate that the antioxidant helps prevent those nasty oxygen- free radicals from transforming LDL, the bad form of cholesterol, into an even more menacing artery clogger...
Through its ability to scavenge free oxygenions, beta carotene could undermine the dangerousoperation of the LDL molecules and thus reducecancer and heart disease risk...