Word: ldl
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...risk for developing CHD is carried out using Framingham risk scoring. The risk factors included in the Framingham calculation are age, total cholesterol, HDL cholesterol, systolic blood pressure, treatment for hypertension, and cigarette smoking. Because of a larger database, Framingham estimates are more robust for total cholesterol than for LDL cholesterol. Note, however, that LDL cholesterol remains the primary target of therapy. The Framingham risk score gives estimates for ?hard CHD? which includes myocardial infarction and coronary death...
Such folks often fall through the cracks. Maybe their LDL, or "bad" cholesterol, is a wee bit high, and their HDL, or "good" cholesterol, is a tad low. Or maybe they have diabetes, which commonly leads to cardiovascular disease, but don't yet show the effects. "I'm not recommending putting [statins] in the drinking water," says Dr. Antonio Gotto, a cardiologist and dean of Weill-Cornell School of Medicine in New York City. "But some 6 million to 7 million more people could benefit from their...
...signs of liver trouble. Most people on the pills report no complaints; those who do commonly list fatigue as the major side effect. Others refer to the peace of mind statins give them. "I feel safer," says Janet Brown, a 57-year-old New Yorker, who has watched her LDL drop from 177 mg/dl to 90 mg/dl. "I'm not walking on life's tightrope when it comes to my cholesterol...
...time being, doctors consider the following individuals to be potential candidates for treatment with statins: those whose LDL is 190 mg/dl or higher; those whose LDL is 160 mg/dl or higher and who have at least two risk factors for heart disease, such as smoking, diabetes or high blood pressure; and those whose LDL is 130 mg/dl or higher and who suffer from heart disease...
Still, some important issues haven't yet been addressed. While omega-3s do indeed lower the level of triglycerides in the blood, they have a tendency to raise the level of LDL, or "bad cholesterol." No one knows if that's a healthy trade-off or for whom. Pregnant women in particular should be careful about fish-oil supplements. Taking cod liver oil, for example, can lead to an overdose of vitamin A, which can in turn cause birth defects. Some nutritionists speculate that omega-6 fatty acids--found in corn and many other vegetable oils--may limit the health...